Syn-Ake
Also known as: Dipeptide Diaminobutyroyl Benzylamide Diacetate, SYN-AKE, beta-Ala-Pro-Dab-NHBn diacetate
Synthetic cosmetic dipeptide (beta-alanyl-prolyl-diaminobutyroyl benzylamide, supplied as the diacetate salt) developed by Pentapharm/DSM to mimic Waglerin-1, a component of temple viper (Tropidolaemus wagleri) venom. It acts as a reversible antagonist of the muscle-type (m) nicotinic acetylcholine receptor, reducing repeated muscle contraction to soften expression wrinkles in a topical, Botox-mimetic fashion. It is a topical cosmetic ingredient, not a therapeutic drug, and has no FDA drug approval; cosmetic anti-wrinkle claims rest mainly on manufacturer studies. The diacetate salt molecular formula is C23H37N5O7 (active dipeptide core C19H29N5O3).
Common research uses
Pricing for Syn-Ake
Live vendor pricing, normalized to $/mg so sizes compare fairly — fused with each seller's Merit trust score and latest independent COA purity. Prices refresh daily.
Average price
$0.42/mg
range $0.42–$0.42/mg
Sellers
2
from $85.00
45-day trend
0%
vs 45-day avg $/mg
1 of 2 sellers have a current price
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✓ verified at source · just now
$0.42/mg 0% vs avg$85.00
200mg
no purity
Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.
COAs for Syn-Ake
1 third-party test across 1 vendor. Each card links to the full report.
12 citations indexed for Syn-Ake
review · 2025
Acetyl Hexapeptide-8 in Cosmeceuticals-A Review of Skin Permeability and Efficacy
Biomimetic peptides represent a growing class of active ingredients in modern cosmeceuticals, designed to mimic the function of the naturally occurring peptides involved in skin homeostasis, repair, and regeneration.
Study · 2025
Discovery of HY•1: A Novel Multifunctional Skincare Ingredient With Antiaging and Skin Repair Properties
Objectives Skin aging, influenced by intrinsic and extrinsic factors, includes photoaging caused by UV radiation, leading to ROS production and skin damage.
in-vitro · 2025
In Vitro Comparative Study of Calcium Hydroxyapatite (Stiim): Conventional Saline Dilution Versus Poly-Micronutrient Dilution
Calcium hydroxylapatite (CaHA) is widely used in aesthetics for its dual role as a dermal filler and biostimulator, promoting collagen and elastin synthesis.
review · 2025
Current Approaches in Cosmeceuticals: Peptides, Biotics and Marine Biopolymers
Today's consumer perception and expectations of personal care have gone beyond merely cleansing, moisturizing, and makeup products, focusing more on the reduction or elimination of signs of aging.
review · 2025
Peptides: Emerging Candidates for the Prevention and Treatment of Skin Senescence: A Review
One class of cosmetic compounds that have raised interest of many experts is peptides. The search for ingredients with good biocompatibility and bioactivity has led to the use of peptides in cosmetic products.
Study · 2024
Anti-aging activity of Syn-Ake peptide by <i>in silico</i> approaches and <i>in vitro</i> tests
The increase in the aging population worldwide has led scientists to turn to research to prevent the aging process. In this context, synthetic peptides emerge as candidate molecules for developing new anti-aging products.