For research use only. Not for human consumption. Not medical advice — consult a licensed clinician.

Nootropic / Cognitive

Pinealon

Also known as: EDR

Pinealon is a synthetic tripeptide (Glu-Asp-Arg) from the Khavinson bioregulator series, studied for its potential role in regulating pineal gland function and neuroprotective signaling pathways in preclinical models.

Real-time market data

Pricing for Pinealon

Live vendor pricing, normalized to $/mg so sizes compare fairly — fused with each seller's Merit trust score and latest independent COA purity. Prices refresh daily.

Average price

$4.17/mg

range $1.70–$9.90/mg

Sellers

40

from $0.00

45-day trend

+11.2%

vs 45-day avg $/mg

35 of 40 sellers have a current price· 23 stale listings hidden (not seen in 7 days)

Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.

Independent evidence

COAs for Pinealon

48 third-party tests across 16 vendors. Each card links to the full report.

All 48 COAs for Pinealon →
Measured purity 76.4%–100.0% across 33 COAs
Measured purity over time
Aggregated · 3rd-party listing
99.00 %
Jun 2026
ILS Labs Strong

For

Pinealon

by Mile High Compounds· batch PNL-010-MH-01

Aggregated · 3rd-party listing
99.41 %
May 2026
Freedom Diagnostics Moderate · HPLC

For

Pinealon

by Peptide Plugs· batch 122-01-DK-GR

Aggregated · 3rd-party listing
76.40 %
Apr 2026
Janoshik Analytical Limited · HPLC

For

Pinealon

by Verified Peptides· batch cmp4wgaw3004bx7rxvog2lrzi

Aggregated · 3rd-party listing
99.55 %
Apr 2026
Janoshik Analytical Limited · HPLC

For

Pinealon

by Verified Peptides· batch PIN0526042OD

Aggregated · 3rd-party listing
99.17 %
Apr 2026
Janoshik Analytical Limited · HPLC

For

Pinealon

by Peptidegurus· batch cmojgr5vi002h9grx6lyxuepc

Aggregated · 3rd-party listing
99.70 %
Apr 2026
BTLabs Moderate · HPLC

For

Pinealon

by Crush Research· batch CR-PIN10-2603-1

Aggregated · 3rd-party listing
99.70 %
Apr 2026
BTLabs Moderate

For

Pinealon

by Crush Research· batch CR-PIN10-2603-1

Aggregated · 3rd-party listing
99.97 %
Apr 2026
Kovera Labs · HPLC

For

Pinealon

by Peptide Partners· batch PN202603

✓ Vendor-published
99.97 %
Apr 2026
Kovera Labs

For

Pinealon

by Peptide Partners· batch PN202603

COA on file
Aggregated · 3rd-party listing
99.15 %
Mar 2026
Vanguard Laboratory Strong

For

Pinealon

by Peptidology· batch 1671

Aggregated · 3rd-party listing
99.72 %
Mar 2026
MDx BioAnalytical Laboratory Strong · HPLC

For

Pinealon

by BioLongevity Labs· batch 41-3-46078

Aggregated · 3rd-party listing
99.80 %
Mar 2026
Vanguard Laboratory Strong

For

Pinealon

by Licensed Peptides· batch 032520261

Aggregated · 3rd-party listing
99.91 %
Mar 2026
Kovera Labs · HPLC

For

Pinealon

by Mile High Compounds· batch PNL-010-MH-01

Aggregated · 3rd-party listing
99.72 %
Feb 2026
Freedom Diagnostics Moderate · HPLC

For

Pinealon

by Peptide Supply Co.· batch PSCPN10001

Aggregated · 3rd-party listing
99.68 %
Feb 2026
Janoshik Analytical Limited · HPLC

For

Pinealon

by Skye Peptides· batch PIN26-20-001

Aggregated · 3rd-party listing
99.56 %
Nov 2025
Janoshik Analytical Limited · HPLC

For

Pinealon

by Verified Peptides· batch 12-25-0320C

✓ Vendor-published
99.56 %
Nov 2025
Janoshik Analytical Limited

For

Pinealon

by Verified Peptides· batch 12-25-0320C

COA on file
✓ Vendor-published
99.56 %
Nov 2025
Freedom Diagnostics Moderate

For

Pinealon

by Ion Peptide· batch PN10-1125

COA on file
Aggregated · 3rd-party listing
99.56 %
Nov 2025
Freedom Diagnostics Moderate

For

Pinealon

by Ion Peptide· batch PN10-1125

Aggregated · 3rd-party listing
99.31 %
Oct 2025
Freedom Diagnostics Moderate

For

Pinalon

by Orbitrex Peptides· batch PIN102025A

✓ Vendor-published
99.83 %
Oct 2025
Freedom Diagnostics Moderate

For

Pinealon

by Ion Peptide· batch PN10-1025

COA on file
Aggregated · 3rd-party listing
99.83 %
Oct 2025
Freedom Diagnostics Moderate

For

Pinealon

by Ion Peptide· batch PN10-1025

Aggregated · 3rd-party listing
99.84 %
Sep 2025
Freedom Diagnostics Moderate · HPLC

For

Pinealon

by Simple Peptide· batch PINE09222025-J

Aggregated · 3rd-party listing
99.89 %
Sep 2025
BioRegen Moderate · HPLC

For

Pinealon

by BioLongevity Labs· batch 41-2-45785

Research depth

12 citations indexed for Pinealon

All research on Pinealon →

review · 2026

Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions

Therapeutic peptides are emerging as promising adjuncts in the management of orthopaedic injuries, grounded in their ability to modulate molecular signaling networks central to cellular medicine.

Study · 2024

Short Peptides Protect Fibroblast-Derived Induced Neurons from Age-Related Changes

Neurons become more vulnerable to stress factors with age, which leads to increased oxidative DNA damage, decreased activity of mitochondria and lysosomes, increased levels of p16, decreased LaminB1 proteins, and the depletion of the dendritic tree.

Study · 2021

Optimization of <i>Jiuzao</i> protein hydrolysis conditions and antioxidant activity <i>in vivo</i> of <i>Jiuzao</i> tetrapeptide Asp-Arg-Glu-Leu by elevating the Nrf2/Keap1-p38/PI3K-MafK signaling pathway

Tetrapeptide Asp-Arg-Glu-Leu (DREL) was isolated from Jiuzao protein hydrolysates (JPHs) by alkaline proteinase (AP) and exhibited antioxidant activity in the HepG2 cell model in the previous study.

review · 2020

EDR Peptide: Possible Mechanism of Gene Expression and Protein Synthesis Regulation Involved in the Pathogenesis of Alzheimer's Disease

The EDR peptide (Glu-Asp-Arg) has been previously established to possess neuroprotective properties. It activates gene expression and synthesis of proteins, involved in maintaining the neuronal functional activity, and reduces the intensity of their apoptosis in in vitro and in vivo studies.

animal · 2019

Role of Mono- and Divalent Ions in Peptide Glu-Asp-Arg-DNA Interaction

The interaction of the regulatory biologically active peptide Glu-Asp-Arg (EDR) with DNA is considered by spectral, NMR, viscosimetry, and molecular dynamics methods. It was shown that EDR can partly penetrate into the major groove of DNA and affect the base atoms, mainly the N7 and O6 of guanine.

cohort · 2016

[Comparative analysis of different methods of geroprotective]

In the monitoring process 110 representatives of different age groups held a comparative analysis of the efficacy and safety of several geroprotective techniques, including the use of dry carbon dioxide baths, hyperbaric oxygen therapy, therapeutic massage and receiving Oligopeptide preparations containing complexes ly…