Question 1

What is Pancragen?

Accepted Answer

Pancragen is a synthetic tetrapeptide (Lys-Glu-Asp-Trp, KEDW) short-peptide bioregulator developed by Vladimir Khavinson and colleagues at the St. Petersburg Institute of Bioregulation and Gerontology, derived from a peptide isolated from bovine pancreatic tissue. The Khavinson group reports it interacts with histones and DNA to modulate tissue-specific gene expression in pancreatic cells, with proposed effects on glucose metabolism and insulin-producing cells. Evidence is confined to single-group preclinical and small clinical studies; it is not FDA-approved and lacks independent Western validation. No CAS Registry Number is listed for this peptide in major chemical databases. Merit Verified tracks independent COA test results for Pancragen from multiple vendors.

Question 2

Which vendors sell Pancragen with independent COA testing?

Accepted Answer

3 vendors in the Merit Verified directory have independent COA evidence on file for Pancragen — 6 COAs total. COA coverage and test dates are listed on the Pancragen page at https://meritverified.org/peptides/pancragen.

Question 3

How do I verify the quality of Pancragen from a vendor?

Accepted Answer

To verify Pancragen quality, look for an independent certificate of analysis (COA) from a third-party lab — not a lab the vendor owns or pays directly. The COA should state the tested compound, lot number, purity percentage (identity and concentration), and the lab's name. Cross-reference the lot number against the vendor's current stock. Merit Verified indexes COAs for Pancragen at https://meritverified.org/peptides/pancragen so you can compare evidence across vendors before buying.

Question 4

What is the regulatory status of Pancragen?

Accepted Answer

Pancragen is classified as research-use only in the Merit Verified registry. In the United States, the FDA removed several peptides including BPC-157, TB-500, and GLP-1 analogues from the 503A compounding ingredient list in April 2026, restricting their use in compounded drugs for human administration. Vendors selling Pancragen for research purposes are not selling it as a drug or supplement; the legal status of purchasing for personal use varies by jurisdiction. Merit Verified does not provide legal or medical advice — confirm current regulatory status with a licensed professional.

	Vendor	Price	$/mg	vs avg	Purity	COAs	Merit
🇺🇸	BioLongevity Labs via Disclosed Labs · just now	$94.97· 20mg	$4.75/mg	+26.1%	99.9%	3	96
🇺🇸	Peptidology ✓ verified at source · just now	$58.99· 23mg	$2.56/mg	-31.9%	99.0%	1	89
🇺🇸	Certified Peptides ✓ verified at source · just now	$105· 20mg	$5.25/mg	+39.4%	99.8%	2	62
	peptidetech.is via Disclosed Labs · just now	$49.99· 20mg	$2.50/mg	-33.6%	—	—	Unscored

Pancragen

Pricing for Pancragen

COAs for Pancragen

12 citations indexed for Pancragen

Challenges of early detection of pancreatic cancer

Analytical Validation of Loss of Heterozygosity and Mutation Detection in Pancreatic Fine-Needle Aspirates by Capillary Electrophoresis and Sanger Sequencing

EUS-guided fine needle aspiration-based clues to mistaken or uncertain identity: serous pancreatic cysts

Extracellular matrix-derived peptide stimulates the generation of endocrine progenitors and islet organoids from iPSCs

Serial EUS-Guided FNA for the Surveillance of Pancreatic Cysts: A Study of Long-Term Performance of Tumor Markers

Pancreatic intraductal tubulopapillary neoplasm progression requiring completion pancreatectomy: A case report and literature review