For research use only. Not for human consumption. Not medical advice — consult a licensed clinician.

Melanocortin

Melanotan II

Also known as: MT-2

Melanotan II (MT-II) is a cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (α-MSH) — Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2 — developed at the University of Arizona in the 1980s by Hruby, Hadley, and colleagues as a candidate photoprotection / sunless-tanning agent. It has never been approved by the FDA or any other regulator for any indication; clinical development was abandoned and it is sold only via grey-market research-chemical channels. Genuine safety signals have been reported, including darkening of existing moles, eruptive atypical nevi, and case reports of new primary melanoma in young tanning-seeking users.

Real-time market data

Pricing for Melanotan II

Live vendor pricing, normalized to $/mg so sizes compare fairly — fused with each seller's Merit trust score and latest independent COA purity. Prices refresh daily.

Average price

$3.64/mg

range $0.00–$6.60/mg

Sellers

73

from $0.00

45-day trend

-3.2%

vs 45-day avg $/mg

67 of 73 sellers have a current price· 48 stale listings hidden (not seen in 7 days)

Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.

Independent evidence

COAs for Melanotan II

57 third-party tests across 22 vendors. Each card links to the full report.

All 57 COAs for Melanotan II →
Measured purity 98.5%–100.0% across 40 COAs
Measured purity over time
Aggregated · 3rd-party listing
98.70 %
Jun 2026
ILS Labs Strong

For

Melanotan-2 acetate

by Voltera Sciences· batch ML20.05.28.26

Aggregated · 3rd-party listing
99.78 %
Jun 2026
ILS Labs Strong

For

Melanotan II

by Crush Research· batch CR-MT2-10-2605-1

Aggregated · 3rd-party listing
99.92 %
May 2026
Janoshik Analytical Limited

For

Melanotan II

by Verified Peptides· batch MT206260510E

Aggregated · 3rd-party listing
98.51 %
May 2026
ILS Labs Strong

For

MLT II

by Ion Peptide· batch MTII20-05072026

Aggregated · 3rd-party listing
98.51 %
May 2026
ILS Labs Strong

For

MLT II

by Ion Peptide· batch MTII20-05072026

Aggregated · 3rd-party listing
99.94 %
May 2026
Freedom Diagnostics Moderate

For

Melanotan-2

by Real Peptides· batch Yellow Cap

Aggregated · 3rd-party listing
99.96 %
Apr 2026
Janoshik Analytical Limited · HPLC

For

Melanotan II

by Skye Peptides· batch MT226-10-001

Aggregated · 3rd-party listing
99.97 %
Apr 2026
Janoshik Analytical Limited · HPLC

For

Melanotan II

by Prime Peptides· batch 3092026MT2

Aggregated · 3rd-party listing
99.73 %
Apr 2026
Janoshik Analytical Limited · HPLC

For

Melanotan II

by Prime Peptides· batch 3132026MT2

Aggregated · 3rd-party listing
99.74 %
Apr 2026
ILS Labs Strong

For

MT2

by Riptide Wellness· batch RWMT2-10-1003

Aggregated · 3rd-party listing
99.14 %
Apr 2026
Chromate Moderate

For

Melanotan II

by Moglabs· batch MT202

Aggregated · 3rd-party listing
99.14 %
Apr 2026
Chromate Moderate

For

Melanotan II

by Arcane Peptides· batch MT202

✓ Vendor-published
99.14 %
Apr 2026
Chromate Moderate

For

Melanotan II

by Arcane Peptides· batch MT202

COA on file
✓ Vendor-published
99.14 %
Apr 2026
MogLabs.bio

For

Melanotan II

by Moglabs· batch MT202

COA on file
Aggregated · 3rd-party listing
99.73 %
Apr 2026
Freedom Diagnostics Moderate · HPLC

For

Melanotan II

by Peptide Plugs· batch 120-A-S

Aggregated · 3rd-party listing
99.00 %
Apr 2026
Ethos Analytics Strong · HPLC

For

Melanotan-2

by OROS Research· batch OR-LPMT2-426-B5

Aggregated · 3rd-party listing
99.92 %
Apr 2026
Kovera Labs · HPLC

For

Melanotan-2

by Glacier Aminos· batch MT210GA-03

Aggregated · 3rd-party listing
99.76 %
Apr 2026
Freedom Diagnostics Moderate · HPLC

For

Melanotan II

by Blank Peptides· batch 665394

Aggregated · 3rd-party listing
99.80 %
Apr 2026
BTLabs Moderate · HPLC

For

Melanotan-2

by Crush Research· batch CR-MT210-2603-1

Aggregated · 3rd-party listing
99.80 %
Apr 2026
BTLabs Moderate

For

Melanotan-2

by Crush Research· batch CR-MT210-2603-1

Aggregated · 3rd-party listing
99.72 %
Mar 2026
Freedom Diagnostics Moderate · HPLC

For

Melanotan II

by Forge Performance Co.· batch Black Cap

Aggregated · 3rd-party listing
99.79 %
Mar 2026
Freedom Diagnostics Moderate

For

Melanotan II

by Kimera Chems· batch KC-MT2-YEL2

Aggregated · 3rd-party listing
99.64 %
Mar 2026
Freedom Diagnostics Moderate · HPLC

For

Melanotan 2

by Peptide Supply Co.· batch MT21003232026

Aggregated · 3rd-party listing
99.97 %
Mar 2026
Kovera Labs · HPLC

For

Melanotan-2

by Mile High Compounds· batch MLN-010-MH-01

Research depth

13 citations indexed for Melanotan II

All research on Melanotan II →

case-report · 2026

Changes in Oral Mucosa Associated with Melanotan II Injections: A Case Report

This case report presents a three-month follow-up of a patient who self-administered Melanotan II injections over a period of 64 days with the goal of achieving a deeper tanning effect. Melanotan II is an unlicensed synthetic peptide analog belonging to the melanocortin hormone family.

rct · 2026

Melanotan II (MT-II) as an Adjunct to NB-UVB Phototherapy for Repigmentation in Stable Nonsegmental Vitiligo

This example interventional study record describes a randomized Phase 2 clinical trial evaluating investigational Melanotan II (MT-II) as an adjunct to standard NB-UVB phototherapy for repigmentation in adults with stable nonsegmental vitiligo.

case-report · 2025

Melanotan II nasal spray: a possible risk factor for oral mucosal malignant melanoma?

The case of a 22-year-old female who developed a mass in the anterior maxilla after using Melanotan II, a nasal spray containing a synthetic analogue of melanocyte-stimulating hormone, is reported. The patient had used the nasal spray for tanning purposes.

animal · 2024

Antidepressant-like and antistress effects of the ACTH(4-10) synthetic analogs Semax and Melanotan II on male rats in a model of chronic unpredictable stress

Current antidepressant therapy shows substantial limitations, and there is an urgent need for the development of new treatment strategies for depression. Stressful events and hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis play an important role in the pathogenesis of depression.

Study · 2024

5-Hydroxypyrroloindoline Affords Tryptathionine and 2,2'-bis-Indole Peptide Staples: Application to Melanotan-II

With peptides increasingly favored as drugs, natural product motifs, namely the tryptathionine staple, found in amatoxins and phallotoxins, and the 2,2'-bis-indole found in staurosporine represent unexplored staples for unnatural peptide macrocycles.

animal · 2023

Melanotan-II reverses memory impairment induced by a short-term HF diet

A high-fat (HF) diet has been shown to increase the risk of neurological impairments and neurodegenerative disorders. The melanotropins used in this study have been associated with diet-related disorders; however, there is an absence of studies on their effect on diet-induced neurobehavioral conditions.