For research use only. Not for human consumption. Not medical advice — consult a licensed clinician.

Melanocortin

Melanotan I

Also known as: Afamelanotide

Melanotan I (Afamelanotide) is a synthetic analog of alpha-MSH that selectively activates MC1R. FDA-approved as Scenesse for erythropoietic protoporphyria (EPP), it is distinct from Melanotan II and is studied for melanogenesis and photoprotection.

Real-time market data

Pricing for Melanotan I

Live vendor pricing, normalized to $/mg so sizes compare fairly — fused with each seller's Merit trust score and latest independent COA purity. Prices refresh daily.

Average price

$4.21/mg

range $0.48–$13.33/mg

Sellers

55

from $0.29

45-day trend

-3.6%

vs 45-day avg $/mg

50 of 55 sellers have a current price· 35 stale listings hidden (not seen in 7 days)

Prices observed from public storefronts (last 24h), normalized to $/mg. "Evidence" is Merit's 0–100 Merit Score, derived only from observable verification evidence (methodology on /about); "Purity" is the latest independent COA. Some buy links are affiliate links — Merit may earn a commission at no extra cost to you, and where a vendor offers one, the code shown gets you a discount at their checkout. Affiliate status never affects price data, ranking, or the Merit Score (full policy on /disclosure). Research use only.

Independent evidence

COAs for Melanotan I

50 third-party tests across 17 vendors. Each card links to the full report.

All 50 COAs for Melanotan I →
Measured purity 99.4%–100.0% across 36 COAs
Measured purity over time
Aggregated · 3rd-party listing
99.77 %
Jun 2026
ILS Labs Strong

For

Melanotan I

by Ion Peptide· batch MLTI10-06102026

Aggregated · 3rd-party listing
99.94 %
May 2026
ILS Labs Strong

For

MLT I

by Ion Peptide· batch MTI10-05072026

Aggregated · 3rd-party listing
99.94 %
May 2026
ILS Labs Strong

For

MLT I

by Ion Peptide· batch MTI10-05072026

Aggregated · 3rd-party listing
99.61 %
Apr 2026
Chromate Moderate

For

Melanotan I

by Moglabs· batch MT102

Aggregated · 3rd-party listing
99.61 %
Apr 2026
Chromate Moderate

For

Melanotan I

by Arcane Peptides· batch MT102

Aggregated · 3rd-party listing
99.55 %
Apr 2026
ILS Labs Strong

For

MT1

by Riptide Wellness· batch RWMT1-10-1002

✓ Vendor-published
99.61 %
Apr 2026
Chromate Moderate

For

Melanotan I

by Arcane Peptides· batch MT102

COA on file
✓ Vendor-published
99.61 %
Apr 2026
MogLabs.bio

For

Melanotan I

by Moglabs· batch MT102

COA on file
Aggregated · 3rd-party listing
99.71 %
Apr 2026
Biogenica Labs · HPLC

For

Melanotan I

by Amino Club· batch MI0001

Aggregated · 3rd-party listing
99.90 %
Apr 2026
BTLabs Moderate · HPLC

For

Melanotan-1

by Crush Research· batch CR-MT110-2603-1

Aggregated · 3rd-party listing
99.90 %
Apr 2026
BTLabs Moderate

For

Melanotan-1

by Crush Research· batch CR-MT110-2603-1

Aggregated · 3rd-party listing
99.82 %
Mar 2026
Freedom Diagnostics Moderate · HPLC

For

Melanotan I

by Simple Peptide· batch MT104232026-4

Aggregated · 3rd-party listing
99.70 %
Mar 2026
Freedom Diagnostics Moderate · HPLC

For

Melanotan 1

by Peptide Supply Co.· batch MT11003232026

Aggregated · 3rd-party listing
99.84 %
Mar 2026
Freedom Diagnostics Moderate

For

Melanotan-1

by Orbitrex Peptides· batch MT1100426

Aggregated · 3rd-party listing
99.98 %
Feb 2026
Kovera Labs · HPLC

For

Melanotan-1

by Mile High Compounds· batch MT1-010-MH-01

Aggregated · 3rd-party listing
99.88 %
Feb 2026
Janoshik Analytical Limited · HPLC

For

Melanotan-1

by Skye Peptides· batch MT126-10-001

Aggregated · 3rd-party listing
99.77 %
Jan 2026
Freedom Diagnostics Moderate

For

Melanotan-1

by Ion Peptide· batch MLT110-011226

Aggregated · 3rd-party listing
99.80 %
Jan 2026
Freedom Diagnostics Moderate

For

Melanotan I

by Kimera Chems· batch KC-MT1-YEL1

Aggregated · 3rd-party listing
99.77 %
Nov 2025
Freedom Diagnostics Moderate · HPLC

For

Melanotan I

by Glacier Aminos· batch MT10GA01

Aggregated · 3rd-party listing
99.60 %
Nov 2025
Janoshik Analytical Limited · HPLC

For

Melanotan 1

by Hydro Research Peptides· batch HYDROCP7QHN3

✓ Vendor-published
99.39 %
Nov 2025
RUO

For

Melanotan I

by Ruo Bio· batch RUOV2912T92H

COA on file
Aggregated · 3rd-party listing
99.46 %
Nov 2025
Freedom Diagnostics Moderate · HPLC

For

Melanotan I

by Peptide Supply Co.· batch cmpa6pnxe000t73rxrsgy091k

Aggregated · 3rd-party listing
99.80 %
Nov 2025
MDx BioAnalytical Laboratory Strong · HPLC

For

MELANOTAN 1

by BioLongevity Labs· batch CONTROL

Aggregated · 3rd-party listing
99.80 %
Oct 2025
MDx BioAnalytical Laboratory Strong · HPLC

For

MELANOTAN 1

by BioLongevity Labs· batch cmojb7eem01azkirxvrxtva2o

Research depth

12 citations indexed for Melanotan I

All research on Melanotan I →

case-report · 2026

Five primary melanomas in situ in a patient with recent tanning bed use, melanotan exposure, and anabolic hormone use

review · 2026

Insights into Tanning Biology and Tanning Products

Objective This systematic review aims to critically assess the literature on the mechanisms of action, clinical uses, formulation strategies, and adverse effects of self-tanning agents, with a focus on dihydroxyacetone (DHA), melanotan, forskolin, and carotenoids.

case-report · 2026

Changes in Oral Mucosa Associated with Melanotan II Injections: A Case Report

This case report presents a three-month follow-up of a patient who self-administered Melanotan II injections over a period of 64 days with the goal of achieving a deeper tanning effect. Melanotan II is an unlicensed synthetic peptide analog belonging to the melanocortin hormone family.

Study · 2025

A single-centre, prospective, qualitative analysis of knowledge, attitudes and behaviour of sunbed use among patients attending a pigmented lesion clinic in a tertiary referral centre

Background Indoor tanning through sunbeds is linked to a heightened risk of skin cancers, particularly cutaneous squamous cell carcinoma and basal cell carcinoma, with significant increases in risk for users aged Objectives To analyse the characteristics, attitudes and behaviours of sunbed users attending an Irish derm…

review · 2024

Journey through the spectacular landscape of melanocortin 1 receptor

The physiological role of α-melanocyte stimulating hormone in regulating integumental pigmentation of many vertebrate species has been recognized since the 1960's. However, its physiological significance for human pigmentation remained enigmatic until the 1990's.

review · 2023

Melanocortin 1 Receptor (MC1R): Pharmacological and Therapeutic Aspects

Melanocortins play crucial roles in regulating the stress response, inflammation, and skin pigmentation. In this review, we focus on the melanocortin 1 receptor (MC1R), a G protein-coupled receptor primarily known for regulating skin pigmentation and exhibiting anti-inflammatory effects.